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Important Limitation SURPASS-2 compared tirzepatide against semaglutide 1mg (the Ozempic dose for diabetes), not the higher 2.4mg dose used for weight loss (Wegovy)

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The primary symptoms of IBS include: Abdominal pain or cramping , often relieved by defecation Bloating and distension Altered bowel habits : diarrhoea (IBS-D), constipation (IBS-C), or mixed patterns (IBS-M) Urgency or a sensation of incomplete evacuation Mucus in stools Symptoms typically fluctuate over time and may be triggered or exacerbated by various factors

Gastroprotective signaling pathway activity